Does Niacinamide contribute to diabetes and insulin resistance?

Vitamin B3 comes in a few forms, with niacin (nicotinic acid (NA)), niacinamide (NAM), nicotinamide riboside (NR) and inositol hexanicotinate being the most famous. As you can see from the … Continue reading Does Niacinamide contribute to diabetes and insulin resistance?

Different fats and inflammation

Let me just start off by saying that fat gain happens mostly in the presence of caloric excess (when more calories are consumed than is being burned). For healthy adipose … Continue reading Different fats and inflammation

Reactive oxygen species created by fats and their affect on insulin signalling

Does fat make you fat? And if the answer is yes then which type of fat is the guilty one? Fat mass expansion in obesity occurs via adipocyte hyperplasia (increased … Continue reading Reactive oxygen species created by fats and their affect on insulin signalling

Metabolic efficiency is more important than mitochondrial quantity

It has been hypothesized that insulin resistance in patients with impaired, or diabetic glucose tolerance, is mediated by a deficiency of mitochondria in skeletal muscle. But it turns out that … Continue reading Metabolic efficiency is more important than mitochondrial quantity