Prolactin, also known as the lactating hormone, is secreted from the pituitary gland. This hormone is able to induce gynecomastia in men. Hyperprolactinemia is associated with inflammatory conditions such as autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis and acute inflammation.
Signs of high prolactin:
- low testosterone
- low libido
- impotence
- gynecomastia
- depressed well-being (low dopamine)
- pain or headache at the top of the head
- visual disturbances (visual field deficits, blurred vision, decreased visual acuity)
- scalp hair loss
- sore/itchy nipples
- osteopenia
- anxiety, depression
- cognitive decline
- fatigue
- emotional instability
- growth arrest and delayed puberty (2)
Main prolactin stimulators include estrogen, low dopamine/high serotonin, high thyrotropin releasing hormone (TRH) due to hypothyroidism, cellular dehydration and cellular damage and physical or emotional stress (1). Prolactin levels between 4-7ng/ml would be optimal. In an earlier article I elaborated more on 5 most effective strategies on lowering prolactin so be sure to check it out.
Prolactin lowering stack:
- Vitex – 400mg per cap, 100 caps
- Mucuna Pruriens – 1200mg (180mg L-dopa extract) per serving, 83 servings
- Royal jelly – 500mg (3:1 concentrate, 6% 10-HDA) per serving, 120 servings (reduce prolactin mRNA) (3)
- Vitamin E – 400IU mixed tocopherol per serving, 120 servings. Start with 1-2 caps daily and work up from there.
- Androsterone – 1mg per drop, 240 drop. Start with 2 drops daily, 1 drop on each nipple, and work up from there if you feel the need.
This complete stack will lower prolactin significantly very quickly, and as a bonus, also lower estrogen and increase testosterone and DHT rapidly.
Good day! I am going to buy zinc gluconate (50 mg), vitamin e (1000iu), mucuna pruriens(1000mg), ashwagandha (1300mg). Is this a good stack for reducing prolactin? And I am planning to add vitex on my prolactin stack but I read that in low dosage in increases prolactin and in high dosage in decreases prolactin. What is that high dosage of vitex to reduce prolactin? Thanks
Hey Marc,
I would rather focus on getting zinc from food, because zinc supplementation can easily cause a imbalancement in the zinc:copper ratio. Milk, red meat and oysters are great sources of both zinc and copper. The vitamin E and mucuna are good choices. The ashwagandha does not directly lower prolactin so I would rather use tribulus terrestris instead with at least 750mg saponin per dose.
It would also be good to focus on getting enough calcium, magnesium and vitamin D (sunlight) in through your diet to lower PTH and TSH as both those are inflammatory and will raise prolactin.
Hope this helps,
Hans
Thanks! But how about the vitex? Some article claims that lower doses of vitex increase prolactin while high doses decrease prolactin. Is this true? If it does lower prolactin, what is the minimum dose of taking vitex? Your opinion will be much appreciated 🙂
Hey Marc. Low doses do appear to increase prolactin, whereas higher doses lower it. 1000-1200mg dose should lower it. However, I would start with the other supplements first and then add vitex later if you’re still struggling to lower prolactin. Improving thyroid function and lowering TSH, estrogen and serotonin are key to lowering prolactin.
Just wondering if Royal Jelly is estrogenic? I have read articles for women with breast cancer not to take it.
According to these studies it has very weak estrogenic effects: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3008742/
https://pubmed.ncbi.nlm.nih.gov/15946813/
However, according to this study, royal jelly inhibits the harmful effects of exogenous estrogen on male reproductive tract.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641457/
Thankyou. Did you happen to have any studies backing up it’s prolactin lowering affect?
Here is a study showing that it reduces pituitary activity and down-regulates prolactin mRNA. https://www.tandfonline.com/doi/abs/10.1271/bbb.80556
Have your ideas about vitex changed?
-tribulus (750mg)
-vitex (1gr)
-vitamin e (400IU)
-royal jelly (500mg)
-mucuna (400mg)
do you think it’s a good stack to lower your prolactin?
It has not. Looks good. I’d add B6 and zinc perhaps, unless you’re already eating oysters and liver frequently. Also, self heal is also a great herb to lower prolactin.
Definitely add B6, although it’s critical that the B6 form is activated (P5P). 25-50mg a day should lower PLT levels by 10-40% and more as time goes by.