Fear is when you are afraid, on edge or feeling uncomfortable in certain circumstances.
It can also make you feel subordinate which makes it easy for others to use/abuse you. Because you’re afraid of what they might do (even if they can’t do much/anything to you).
This fear creates inner tension and anxiety which prevents you from doing everyday tasks normally. It can also make you want to stay at home and go into complete avoidance.
Not much can be done in such a state, especially if you want to grow personally or in your business.
Causes of fear
Fear or any mental condition is caused/worsened by your hormones and neurotransmitters.
Excess glutamate, CRH, estrogen (R), noradrenaline and adrenaline can cause fear and contribute to PTSD and similar milder symptoms.
That’s why things like magnesium, theanine, zinc, clonidine, beta-blockers, etc., are all great against fear.
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The best anti-fear hormone
Instead of addressing all the pathways above, we can specifically increase one pathway that will put a brake on all the above.
That hormone is DHT (dihydrotestosterone).
DHT by binding to the androgen receptor and also converting to its metabolite 3alpha-diol (GABA agonist) has strong anti-anxiety, anti-fear, anti-avoidance, anti-learned helplessness and anti-freeze effects (R, R).
Other 5 alpha-reduced steroids (such as androsterone and 3alpha-diol), also have strong anti-anxiety and anti-depressant effects, because they are strong GABA agonists.
Activation of androgen receptors
A decrease in androgen receptor density in the hippocampus due to stress results in increased anxiety and impaired learning (R). So this means that some men need higher androgens for it to have a strong anti-anxiety and anti-fear effect. Androgen can also increase androgen receptors.
Improves brain blood flow
Testosterone improves blood flow in the brain via activation of the androgen receptors (R).
Enhancing neurogenesis and improve mitochondrial function
It most likely comes down to the fact that DHT is protective to mitochondrial function as that’s where all the action/magic happens. Low mitochondrial function leads to all kinds of issues including cognitive decline. That’s why I focus on the root – optimizing mitochondrial function.
“The levels of sex hormones in elderly people decrease with age, and low levels of androgens in older male individuals have been closely linked to the development of cognitive impairment. Basic studies have shown that androgens have neuroprotective effects and that androgen deficiency impairs cognitive function by increasing oxidative stress and decreasing synaptic plasticity, among other effects.” (R)
“Androgens can improve the biological activity of cells by increasing the production of ATP in the mitochondria and can also increase antioxidant activity to regulate redox homeostasis, thereby exerting a neuroprotective effect (9, 10). The cerebral vasculature is also the target of androgens, which increase vascular tone, enhance angiogenesis and cerebral vascular remodeling, reduce vascular damage by attenuating oxidative stress, and maintain the integrity of the blood–brain barrier, thereby exerting additional neuroprotective effects (11). In the hippocampus of the brain, testosterone can improve synaptic plasticity and prevent neuronal cell death. DHT induces circuit modifications by changing the number of excitatory spine synapses in a paracrine manner, which in turn affects the cognitive function of the brain (12).” (R)
For me, DHT is calming and eliminates any fear or uneasiness. It feels like it makes you anhedonic to negative outcomes, such as intimidation, stage fright, caring what others think, etc.
But it doesn’t blunt the good feelings. It feels like a dopaminergic anhedonic. As if your feelings are stoned to fear and anxiety.
DHT also has a motivating factor to it, so that you just do what has to be done and you don’t feel overwhelmed or drained by it.
All in all, very good.
A few ways to increase or experience its effects are via:
- 11-keto DHT – I use only 1mg in my navel in the mornings and that’s all I need. Powerful stuff.
- Topical DHEA
- Creatine around a workout
- Butea superba
- Eating carbs (insulin and IGF-1 increase 5AR)
- Eating meat
Read here on more ways on how to increase your DHT:
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