Medical institutions, as well as common research, will teach you that PUFAs are highly essential for brain function, mainly because they are found in such high concentrations within the brain. To assume that PUFAs are essential because they are found in such high concentrations in the brain, is like assuming that because tics are so…
Tag: Prostaglandins
PUFA dangers Part 2: Lipid peroxidation and prostaglandins
So now lets get to the part about why PUFAs are so bad. PUFA dangers The predominant omega 6 fatty acid is arachidonic acid (AA), which can be reduced (i) via enzymatic peroxidation to prostaglandins, leukotrienes, thromboxanes, and other cyclooxygenase, lipoxygenase or cytochrome P-450 derived products or (ii) via nonenzymatic peroxidation to MDA, 4-HNE, isoprostanes, and other lipid…
Ketogenic diet – is it safe? (lipid peroxidation, prostaglandins, inflammation)
Two aspects might be of concern when eating a ketogenic diet… Increase ROS due to more saturated fat consumption and more lipid peroxidation due to more unsaturated fat ingestion. Let’s start with the increase in ROS 1 glucose molecule produces 10 NADH and 2 FADH2 through glycolysis and the TCA cycle. During beta-oxidation, for…